Health, Zoomer Report

Protein that Causes High Cholesterol

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Here’s important news in the fight against cardiovascular disease. Canadian researchers have discovered the protein that causes high cholesterol and this could lead to new revolutionary drugs. The researchers from McMASTER UNIVERSITY found that a protein called resistin, which is secreted by fat tissue, causes high levels of bad cholesterol, or LDL .

Resistin increases the production of LDL and impairs LDL receptors in the liver, making it more difficult for the liver to clear bad cholesterol from the body. The discovery is an important finding because there have been very few factors or proteins identified that directly affect blood LDL cholesterol levels.

The study showed that resistin blocks drugs called statins from working effectively. Statins are used to lower cholesterol and other fats in the body, and this could explain why these drugs don’t work for about 40 per cent of people taking them. The scientists say this gives new hope to those people.

About 40 per cent of Canadians have high cholesterol levels. Cutting cholesterol is key because high levels can lead to a buildup of plaque in the artery walls and narrow the arteries, making it tougher for blood to flow through a person’s heart and body.

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